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Environmental Epigenetics: New Frontiers in Autism Research

This symposium brought together scientists from multiple disciplines to consider how environmental epigenetics may be playing a role the genesis of some forms of neurodevelopmental disability, including autism spectrum disorders.

March 22-23, 2013
UC Davis MIND Institute, Sacramento, CA

Please explore this website for the meeting summary, presentation videos and summaries, agenda, featured speaker information, poster presentation abstracts, a glossary of terms, and research links.

Gene-environment interaction has important implications for autism causation research. We thank our participants, who are doing cutting-edge work in this emerging field, and invite you to learn more.

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About

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Non-genetic factors such as environmental exposures can change the behavior of genes. Environmental epigenetics is the study of how external signals modify gene expression.

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Speakers

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Experts from many fields, including biology, epigenetics, reproduction, endocrinology, molecular biology and epidemiology shared current knowledge and discussed future directions.

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Symposium Archives

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Get it here! Summary of Major Themes PDF, presentation videos, Poster Abstracts PDF and Final Agenda PDF.  

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Videos and summaries of presentations

Symposium summary here: Summary Themes PDF

Videos of presentations here: http://www.ucdmc.ucdavis.edu/mindinstitute/videos/video_es.html (Once on the page, please scroll down to see all videos)

 
Who says you can’t have a genetic epidemic?
Jill Escher, Escher Fund for Autism

 

 

Environment, neurodevelopment, and opportunities for prevention

Tracey Woodruff, PhD, MPH, Program on Reproductive Health and the Environment, UCSF

 

 

Perinatal environmental exposures and lifecourse health effects
Dana Dolinoy, PhD, University of Michigan School of Public Health

 

 

Evolutionary implications for a new world of contamination

David Crews, PhD, Section of Integrative Biology, University of Texas at Austin

 

 

Environmental induced epigenetic transgenerational inheritance of disease

Michael Skinner, PhD, Washington State University

 

 

A remodeled germline epigenome: the ultimate gift to our children and grandchildren

Amander Clark, PhD, UCLA

 

 

How might epigenetics relate to the etiology of ASD?

Dani Fallin, PhD, Johns Hopkins Bloomberg School of Public Health

 

 

Epigenetic inheritance of complex behaviors and their alteration by traumatic stress in mammals

Prof. Isabelle Mansuy, Brain Research Institute, University of Zurich

 

 

Neuroendocrine disruptors, epigenetics and neurodevelopment

Andrea Gore, PhD, University of Texas at Austin

 

 

Prenatal exposures: An unrecognized multigenerational epidemic

June Reinisch, PhD and Erik L. Mortensen, CanD, University of Copenhagen Prenatal Development Project

 

 

A role for assisted reproduction technology (ART) in the etiology of ASD?

Rosanna Weksberg, MD PhD, University of Toronto

 

 

BPA, social behavior, and epigenetics in juvenile mice

Emilie Rissman, PhD, University of Virginia

 

 

PBDE exposure, sex differences and epigenetics in an animal model of ASD
Janine LaSalle, PhD, Medical Microbiology and Immunology, UC Davis School of Medicine

 

 

Counseling the pregnant woman: Focus on SSRI antidepressants

Adam Urato, MD, Chairman, Dept. of OB/GYN, MetroWest Medical Center, Assistant Professor, Tufts Medical Center

 

 

These webcasts are intended for personal, non-commercial, educational use.  Please do not re-broadcast, re-encode, or otherwise distribute these webcasts without prior written permission from Autism Speaks and the UC Davis MIND Institute. The opinions and views expressed herein are provided for informational purposes only, and the statements of the designated speakers do not necessarily reflect the opinions or views of the event sponsors.

Sponsored by:  Autism Speaks, the UC Davis MIND Institute, and the Escher Fund for Autism

 

Poster presentations


Thank you to our wonderful poster presenters!  Please see a summary of poster presentations here: Poster Abstracts or click on Learn More for the webpage.

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Environmental Epigenetics Glossary

For many in the autism community, epigenetics is a new paradigm involving unfamiliar terms. Click on Learn More for a glossary of some terms to help foster understanding of basic concepts discussed during the symposium:

Body burden ... Chromatin ... Copy number variation ... DNA hypomethylation ... DNA methylation ... Endocrine disruptors ... Epigenome ... Epimutation ... Folate ... Germline modification ... Germline reprogramming ... Imprinting ... Transgenerational epigenetic inheritance .. Windows of susceptibility

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